Okolona was approved as a Mississippi Small Town Main Street community in June 2000. The Main Street Program is built upon a four-point approach, which depends upon the full support and commitment of public and private sectors. The four points are organization, promotion, design, and economic-restructuring.

• Organization works to strengthen the relationships among the leadership of elected officials, business and community leadership and assist in the effective management of resources within the central business district.
• Promotion works to improve and unify the image of downtown and to market it as a destination.
• Design works toward the improvement of downtown's physical appearance by assisting in the careful refurbishing of buildings, signs and public areas.
• Economic Restructuring works to redefine downtown's position in the local trade area by recruiting new and complementary businesses.